In the Adey Lab, we seek to answer fundamental questions in biology pertaining to cell identity and cell fate specification. Specifically, we aim to apply systems-based logic to understand the most basic circuitry of a cell and how the configuration of that circuitry locks it in place in its functional role, or pushes it along from one state to another. To accomplish this task, we are leveraging and developing cutting edge technologies to provide the unprecedented resolution and throughput that is required. This includes several single cell strategies to profile genetic and epigenetic properties at high throughput such as single cell ATAC-seq, whole genome sequencing, single cell DNA Methylation, and other important marks that define the epigenetic landscape